Pathogenesis of Scabies



Image taken from the book
Scabies Mite (Adult Female)
Gravid female mites is necessary for spread (transmission) of infection. The female mites measuring 0.3 to 0.4 millimeters (mm) in length, oval in shape, they are ventrally flattened and have a convex dorsal surface. Mite have four pairs of legs.

Fertilized female mites burrow for a month superficially beneath the stratum corneum of the skin where they deposit two or three eggs per day for six to eight weeks. Larvae that hatches from these eggs mature in a series of molts in about two weeks and after that emerge to the surface of the skin, becomes adult, where they mate and subsequently reinvade the skin of the same or another host. Transmission of fertilized female mite from one person to another occurs by intimate personal contact and is facilitated by crowding, uncleanliness.

The itching and rash associated with Scabies derive from a sensitization reaction to the excreta that the mite deposit  in its burrows.

These mites can not survive off the human body for more than 48 hours and can not reproduce off the body.
 
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